000			01572cam a2200229 i 4500
020			_a9780367542863
020			_a9780367542870
082	0	0	_a572.8/8078 _223 _bVAS-C
245	0	0	_aCRISPR-/Cas9 based genome editing for treating genetic disorders and diseases / _ceditor, Luis María Vaschetto, Oncativo, Córdoba, Argentina.
250			_aFirst edition.
260			_bCRC Press, _c2022
300			_avi, 262 pages : _billustrations ;
500			_a"A Science Publishers book."
504			_aIncludes bibliographical references and index.
520			_a"The field of genome editing has progressed incredibly in the last few years mainly due to the emergence of versatile genome editing tools such as endonuclease-based systems which can be used to efficiently edit gene sequences in a targeted fashion. The CRISPR/Cas9 genome editing system represents an easy-to-use and low-cost alternative for gene editing that has revolutionized research in many different areas ranging from medicine and biotechnology, by democratizing genome editing in laboratories around the world. Remarkably, the CRISPR/Cas9-mediated gene editing system can be used to replace/correct nucleotide mutations associated with genetic disorders and diseases. The objective of this book is to shed light on the CRISPR/Cas9 system and related genome engineering technologies in therapeutics and gene therapy"--
650	1	2	_aCRISPR-Cas Systems
650	2	2	_aCRISPR-Associated Protein 9
650	2	2	_aGene Editing
650	2	2	_aGenetic Therapy
700	1		_aVaschetto, Luis M.
942			_cBK
999			_c670122 _d670122