000 | 01044cam a22001818i 4500 | ||
---|---|---|---|
999 |
_c584859 _d584859 |
||
020 | _a9780815345565 | ||
082 | 0 | 0 |
_a615.19 _bDUN-M |
100 | 1 | _aDunlap, Norma, | |
245 | 1 | 0 |
_aMedicinal chemistry / _cNorma Dunlap, Donna M. Huryn. |
260 |
_aNew York: _bGarland Science, _c2018. |
||
300 | _axii, 495 p. | ||
504 | _aIndex. | ||
505 | 0 | _aHistorical perspective and overview of drug discovery -- Drug discovery: hit and lead discovery -- Drug discovery: optimization of lead properties -- Medicinal chemistry strategies used in lead optimization -- The process of developing a drug from an optimized lead: -- Receptors as drug targets -- Enzymes as drug targets -- Protein-protein interactions and lipids as drug targets -- DNA and RNA as drug targets -- Anti-cancer drugs -- Infectious diseases I: antiviral and antifungal drugs -- Infectious diseases II: antibacterial and antiparasitic drugs -- Drugs acting on the CNS. | |
650 | 0 | _aPharmaceutical chemistry. | |
650 | 0 | _aChemotherapy. | |
700 | 1 | _aHuryn, Donna M., | |
942 | _cBK |