000 01044cam a22001818i 4500
999 _c584859
_d584859
020 _a9780815345565
082 0 0 _a615.19
_bDUN-M
100 1 _aDunlap, Norma,
245 1 0 _aMedicinal chemistry /
_cNorma Dunlap, Donna M. Huryn.
260 _aNew York:
_bGarland Science,
_c2018.
300 _axii, 495 p.
504 _aIndex.
505 0 _aHistorical perspective and overview of drug discovery -- Drug discovery: hit and lead discovery -- Drug discovery: optimization of lead properties -- Medicinal chemistry strategies used in lead optimization -- The process of developing a drug from an optimized lead: -- Receptors as drug targets -- Enzymes as drug targets -- Protein-protein interactions and lipids as drug targets -- DNA and RNA as drug targets -- Anti-cancer drugs -- Infectious diseases I: antiviral and antifungal drugs -- Infectious diseases II: antibacterial and antiparasitic drugs -- Drugs acting on the CNS.
650 0 _aPharmaceutical chemistry.
650 0 _aChemotherapy.
700 1 _aHuryn, Donna M.,
942 _cBK