000 01723cam a22001938i 4500
020 _a9781107052734 (hardback)
082 0 0 _a571.6 SHE
100 1 _aSheetz, Michael P.,
245 1 4 _aThe cell as a machine /
_cMichael Sheetz, Columbia University, New York, Hanry Yu, National University of Singapore.
260 _aUK:
_b Cambridge University Press;
_c2018.
300 _a425 pages cm.
490 0 _aCambridge texts in biomedical engineering
504 _aIncludes bibliographical references and index.
520 _a"This unique introductory text explains cell functions using the engineering principles of robust devices. Adopting a process-based approach to understanding cell and tissue biology, it describes the molecular and mechanical features that enable the cell to be robust in operating its various components, and explores the ways in which molecular modules respond to environmental signals to execute complex functions. The design and operation of a variety of complex functions are covered, including engineering lipid bilayers to provide fluid boundaries and mechanical controls, adjusting cell shape and forces with dynamic filament networks, and DNA packaging for information retrieval and propagation. Numerous problems, case studies and application examples help readers connect theory with practice, and solutions for instructors and videos of lectures accompany the book online. Assuming only basic mathematical knowledge, this is an invaluable resource for graduate and senior undergraduate students taking single-semester courses in cell mechanics, biophysics and cell biology"--
650 0 _aCells
650 0 _aCell physiology.
700 1 _aYu, Hanry,
942 _cBK
999 _c584745
_d584745