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020 _a9781466594906 (hardback : acidfree paper)
020 _a146659490X (hardback : acidfree paper)
082 0 0 _a572
245 0 0 _aMicrofluidics and nanotechnology :
_bbiosensing to the single molecule limit /
_cedited by Eric Lagally, Western Governers University, Krzysztof Iniewski, CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada.
300 _axvi, 274 pages :
_billustrations ;
490 0 _aDevices, circuits, and systems
504 _aIncludes bibliographical references and index.
505 _aMICROFLUIDUCS--NANOFLUIDICS
520 _a"Preface Microtechnology and more recent nanotechnology methods have enabled the fabrication of a wide variety of new chemical and biological sensors. These sensors demonstrate exquisite sensitivity and low limits of detection, enabling exploration of new scientific frontiers. In particular, the novel physics that emerges at small length scales allows parallel, mass-fabricated sensors for detection to both single-cell and single-molecule limits. Stochastic differences between individual cells and molecules have been shown to play important roles in larger biological systems, and these novel sensors have begun to test and elucidate these effects. This book focuses on the combination of soft materials like elastomers and other polymers with materials like semiconductors, metals, and glass to form integrated detection systems for biological and chemical targets. Microfluidic advances in this arena include systems for forming and analyzing tiny droplets (so-called droplet microfluidics); the combination of electrostatic and dielectrics to manipulate droplets on the microscale; miniaturized separation systems, including electrophoresis, for detecting a wide range of genetic targets from single cells; and novel optical and mechanical detection methods at the single-cell and single-molecule scales. This book represents a snapshot of the state of the art from the world's leading microfluidics and nanotechnology laboratories. The combination of different materials at both of these length scales is driving a powerful new set of scientific inquiries that have to date been impossible to address using other technologies. The book is arranged in two major sections. In Part I, the authors discuss a number of unique detection technologies"--
650 0 _aBiosensors.
650 0 _aBiomolecules.
650 0 _aCytochemistry.
650 0 _aMicrofluidics
650 0 _aMolecular recognition.
650 0 _aNanofluids.
650 7 _aMEDICAL / Biotechnology.
650 7 _aSCIENCE / Chemistry / Analytic.
650 7 _aTECHNOLOGY & ENGINEERING / Sensors.
700 1 _aLagally, Eric.
856 4 2 _uhttp://images.tandf.co.uk/common/jackets/websmall/978146659/9781466594906.jpg
942 _cBK