000 01347nam a2200169Ia 4500
999 _c295431
_d295431
020 _a9789381269985
082 _a615.19 SIL-O
100 _aRichard B. Silverman
245 _aThe Organic Chemistry of Drug Design and Drug Action
250 _a2nd ed
260 _a Amsterdam ; Boston
_bElsevier Academic Press
_c2004
300 _a xix, 617 p., [12] pages of plates : ill (some color) ; 27 cm
505 _a Introduction -- Drug discovery, design, and development -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- DNA-interactive agents -- Drug metabolism -- Prodrugs and drug delivery systems.
520 _a Combining two essential Academic Press books, this bundle provides reference information for drug discovery researchers and professionals at a great price. Drug Like Properties provides drug discovery scientists and students with a practical understanding of property fundamentals and structure modification strategies that can be applied to improving drug leads. The Organic Chemistry of Drug Design and Drug Action represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules.
650 _aPharmaceutical chemistry. Bioorganic chemistry. Molecular pharmacology. Drugs --Design.
942 _cBK