000 01685nam a2200169Ia 4500
999 _c294722
_d294722
020 _a0854046453
082 _a 615.19 HAN-C
100 _a James Ralph Hanson
245 _aChemistry and Medicines: An Introductory Text
250 _a1
260 _a Cambridge, UK
_bRSC Publishing,
_c2006
300 _a x, 156 p. : ill
505 _a General principles of medicinal chemistry -- Neurotransmitters as targets -- Medicinal chemistry and the central nervous system -- Local and circulatory hormone targets -- Anti-infective agents -- Cancer chemotherapy.
520 _aMedicinal chemistry incorporates bio-organic chemistry, organic synthetic methods, physical organic chemistry and organic reaction mechanisms. These areas of chemistry are crucial to the design and synthesis of new drugs, both in academia and the pharmaceutical industry. Chemistry and Medicines: An Introductory Text provides a general introduction to this fascinating subject. The first chapters contain a brief historical introduction followed by a description of the chemical features involved in the adsorption, distribution, metabolism and excretion of a drug. The remaining chapters describe the chemistry underlying the design and synthesis of some of the key drugs used to combat some major diseases of the peripheral and central nervous system, infectious diseases and cancers. A glossary and suggestions for further reading complete this textbook. The book is aimed at those studying advanced undergraduate and postgraduate courses in medicinal chemistry
650 _a Pharmaceutical chemistry. Chemistry, Pharmaceutical. Pharmaceutical Preparations -- chemistry.
942 _cBK