| 000 | 01874nam a2200169Ia 4500 | ||
|---|---|---|---|
| 999 |
_c293787 _d293787 |
||
| 020 | _a9781584886426 | ||
| 082 | _a570.285 ALO-I | ||
| 100 | _aUri Alon | ||
| 245 | _aAn Introduction to System Biology | ||
| 260 |
_a Boca Raton, FL _bChapman & Hall/CRC _c2007 |
||
| 300 | _a xvi, 301 p., [4] p. of plates : ill. (some col.) ; 26 cm. | ||
| 490 | _a Chapman and Hall/CRC mathematical & computational biology series, 10. | ||
| 505 | _a Ch. 1. Introduction -- Ch. 2. Transcription networks : basic concepts -- Ch. 3. Autoregulation : a network motif -- Ch. 4. The feed-forward loop network motif -- Ch. 5. Temporal programs and the global structure of transcription networks -- Ch. 6. Network motifs in developmental, signal transduction, and neuronal networks -- Ch. 7. Robustness of protein circuits : the example of bacterial chemotaxis -- Ch. 8. Robust patterning in development -- Ch. 9. Kinetic proofreading -- Ch. 10. Optimal gene circuit design -- Ch. 11. Demand rules for gene regulation -- Ch. 12. Epilogue : simplicity in biology. | ||
| 520 | _aThis book presents recently discovered design principles that govern the structure and behavior of biological networks such as gene circuits, highlighting simple, recurring circuit elements that make up the network. It provides a quantitative theory for which circuits are found in a given environment and a mathematical framework for understanding and even designing biological circuits. The book requires only basic mathematics and includes a review of the necessary background material. It fills a significant need for a textbook and introduction to the concepts, principles, and mathematical tools that will form the basis of future developments in the field | ||
| 650 | _a Systems biology. Computational biology. Biological systems -- Mathematical models. View all subjects | ||
| 942 | _cBK | ||