000 01176nam a2200145Ia 4500
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020 _a1402001363
082 _a572.8/633 KOS-H
245 _aHidden Markov Models for Bioinformatics
250 _a1
300 _a416
520 _aThe purpose of this book is to give a thorough and systematic introduction to probabilistic modeling in bioinformatics. The book contains a mathematically strict and extensive presentation of the kind of probabilistic models that have turned out to be useful in genome analysis. Questions of parametric inference, selection between model families, and various architectures are treated. Several examples are given of known architectures (e.g., profile HMM) used in genome analysis. Audience: This book will be of interest to advanced undergraduate and graduate students with a fairly limited background in probability theory, but otherwise well trained in mathematics and already familiar with at least some of the techniques of algorithmic sequence analysis.
650 _aNucleotide sequence -Mathematical models. Nucleotide sequence -Statistical methods. Markov processes.
942 _cBK
999 _c293709
_d293709