000			02094cam a2200253 i 4500
999			_c255740 _d255740
020			_a9780815345992 (pbk. : alk. paper)
020			_a0815345992 (pbk. : alk. paper)
020			_a9781138612914 (hardback : alk. paper)
020			_a113861291X (hardback : alk. paper)
082	0	0	_a572.8 _bGRA-D
245	1	0	_aDNA repair and replication : _bmechanisms and clinical significance / _cedited by Roger J. A. Grand, John J. Reynolds.
260			_aFlorida: _bCRC Press, _c2019.
300			_axvi, 348 pages : _bcolor illustrations ;
500			_a"A Garland Science book."
504			_aIncludes bibliographical references.
505	0		_aDNA replication and cell cycle control / Sara Priego Moreno, Rebecca M. Jones, and Agnieszka Gambus -- DNA replication termination and genomic instability / Rebecca M. Jones, Sara Priego Moreno, and Agnieszka Gambus -- Mechanisms of DNA damage tolerance / Anastasia Zlatanou and Cyrus Vaziri -- Repair of DNA adducts and single strand breaks / Alicja Winczura and John J Reynolds -- Homologous recombination at replication forks / Eva Petermann -- Mechanisms of double strand break repair by non-homologous end-joining / Michal Malewicz -- Protein methylation and the DNA damage response / Martin Higgs and Clare Davies -- Ubiquitin, SUMO, and the DNA double strand break response / R.M. Densham, A.J. Garvin, and J.R. Morris -- Transcription in the context of genome stability maintenance / Marco Saponaro -- RNA binding proteins and the DNA damage response / Roger Grand -- DNA replication and inherited human disease / John J. Reynolds and Grant S. Stewart -- Genetics of ataxia telangiectasia and AT like disorders / A. Malcolm R. Taylor -- DNA repair mechanisms in stem cells and its implications during ageing / Rachel Bayley and Paloma Garcia -- Targeting replication stress in sporadic tumours / Marwan Kwok and Tatjana Stankovik.
650	1	2	_aDNA Repair
650	2	2	_aDNA Replication
650	2	2	_aGenomic Instability
650	2	2	_aMolecular Targeted Therapy
700	1		_aGrand, R. J. A.
700	1		_aReynolds, John J.
942			_cBK