000 01133cam a22002174a 4500
020 _a9781936113491 (hard cover : alk. paper)
020 _a9781936113507 (pbk. : alk. paper)
082 0 0 _a572.8/6459 STO
100 1 _aStormo, Gary.
245 1 0 _aIntroduction to protein-DNA interactions :
_bstructure, thermodynamics, and bioinformatics /
_cGary D. Stormo.
260 _aCold Spring Harbor, N.Y. :
_bCold Spring Harbor Laboratory Press,
_cc2013.
300 _ax, 198 p. :
_bcol. ill. ;
504 _aIncludes bibliographical references and index.
505 0 _aImportance of protein/DNA interactions -- The structure of DNA -- Protein structure and DNA recognition -- Sequence-specific interactions in protein/DNA complexes -- Binding affinity, cooperativity, and specificity -- Energetics and kinetics of binding -- Bioinformatics of DNA-binding sites -- Bioinformatics of transcription factors and recognition models -- Bioinformatics of gene regulation.
650 1 2 _aDNA-Binding Proteins
650 2 2 _aBinding Sites.
650 2 2 _aDNA
650 2 2 _aProtein Binding.
650 2 2 _aTranscription Factors.
942 _cBK
999 _c255350
_d255350