Principles of pharmacogenomics : pharmacokinetic, pharmacodynamic, and clinical implications / Y.W. Francis Lam, Larisa H. Cavallari.

Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation \includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunities within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference. Multi-contributed book and chapters are written by contributors who are experts in their field. Provides perspectives from those involved in all aspects of pharmacogenomics including academic, regulatory, economic, industry and medical to illustrate how all of the pieces fit together and where the challenges may be. Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications. Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research.