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Introduction to Mathematical Methods in Bioinformatics/ by Alexander Isaev

By: Material type: TextTextPublication details: Berlin ; New York : Springer, 2004.Description: xiii,294pISBN:
  • 8181284992
Subject(s): DDC classification:
  • 572.0285 ISA/I
Contents:
1. Introduction : biological sequences -- 2. Sequence alignment -- 3. Markov chains and hidden Markov models -- 4. Protein folding -- 5. Phylogenetic reconstruction -- 6. Elements of probability theory -- 7. Significance of sequence alignment scores -- 8. Elements of statistics -- 9. Substitution matrices.
Summary: This book looks at the mathematical foundations of the models currently in use. This is crucial for the correct interpretation of the outputs of the models. A bioinformatician should be able not only to use software packages, but also to know the mathematics behind these packages." "From this point of view, mathematics departments throughout the world have a major role to play in bioinformatics education by teaching courses on the mathematical foundations of the subject. Based on the courses taught by the author the book combines several topics in biological sequence analysis with mathematical and statistical material required for such analysis."--Jacket
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Holdings
Item type Current library Home library Call number Status Date due Barcode
Book Book Study Centre Alappuzha, University of Kerala Study Centre Alappuzha, University of Kerala 572.0285 ISA/I (Browse shelf(Opens below)) Available USCA3821

1. Introduction : biological sequences --
2. Sequence alignment --
3. Markov chains and hidden Markov models --
4. Protein folding --
5. Phylogenetic reconstruction --
6. Elements of probability theory --
7. Significance of sequence alignment scores --
8. Elements of statistics --
9. Substitution matrices.

This book looks at the mathematical foundations of the models currently in use. This is crucial for the correct interpretation of the outputs of the models. A bioinformatician should be able not only to use software packages, but also to know the mathematics behind these packages." "From this point of view, mathematics departments throughout the world have a major role to play in bioinformatics education by teaching courses on the mathematical foundations of the subject. Based on the courses taught by the author the book combines several topics in biological sequence analysis with mathematical and statistical material required for such analysis."--Jacket

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