Algorithms in Bioinformatics : A practical introduction
Material type: TextSeries: Chapman and Hall/CRC mathematical & computational biology seriesPublication details: Boca Raton Chapman & Hall/CRC Press 2010Description: xvii, 381 p. : ill (some color) ; 24 cmISBN:- 9781420070330
- 572.80285 SUN-A
Item type | Current library | Home library | Call number | Status | Date due | Barcode | |
---|---|---|---|---|---|---|---|
Book | Dept. of Computational Biology and Bioinformatics Processing Center | Dept. of Computational Biology and Bioinformatics | 572.80285 SUN-A (Browse shelf(Opens below)) | Available | DCB1704 |
Introduction to molecular biology -- Sequence similarity -- Suffix tree -- Genome alignment -- Database search -- Multiple sequence alignment -- Phylogeny reconstruction -- Phylogeny comparison -- Genome rearrangement -- Motif finding -- RNA secondary structure prediction -- Peptide sequencing -- Population genetics.
"Algorithms in Bioinformatics: A Practical Introduction provides an in-depth introduction to the algorithmic techniques applied in bioinformatics. For each topic, the author clearly details the biological motivation and precisely defines the corresponding computational problems, and includes detailed examples to illustrate each algorithm." "The book begins with basic molecular biology concepts. It then describes ways to measure sequence similarity, presents simple applications of the suffix tree, and discusses the problem of searching sequence databases. After introducing methods for aligning multiple biological sequences and genomes, the text explores applications of the phylogenetic tree, methods for comparing phylogenetic trees, the problem of genome rearrangement, and the problem of motif finding. It also covers methods for predicting the secondary structure of RNA and for reconstructing the peptide sequence using mass spectrometry. The final chapter examines the computational problem related to population genetics."--Jacket.
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