TY - BOOK AU - Vaschetto,Luis M. TI - CRISPR-/Cas9 based genome editing for treating genetic disorders and diseases SN - 9780367542863 U1 - 572.88078 VAS 23 PY - 2022/// CY - London PB - CRC Press KW - CRISPR-Cas Systems KW - CRISPR-Associated Protein 9 KW - Gene Editing KW - Genetic Therapy N1 - "A Science Publishers book."; Includes bibliographical references and index N2 - "The field of genome editing has progressed incredibly in the last few years mainly due to the emergence of versatile genome editing tools such as endonuclease-based systems which can be used to efficiently edit gene sequences in a targeted fashion. The CRISPR/Cas9 genome editing system represents an easy-to-use and low-cost alternative for gene editing that has revolutionized research in many different areas ranging from medicine and biotechnology, by democratizing genome editing in laboratories around the world. Remarkably, the CRISPR/Cas9-mediated gene editing system can be used to replace/correct nucleotide mutations associated with genetic disorders and diseases. The objective of this book is to shed light on the CRISPR/Cas9 system and related genome engineering technologies in therapeutics and gene therapy"-- ER -