DNA Modification Detection Methods/ 
Edited by Bi-Feng Yuan 
 - New York:  Humana Press;  2022. 
 - 194p.  HB 
<br/><br/>Includes Bibiliographical References and Index 
<br/><br/>Understanding the functional roles of DNA modifications relies on the accurate detection, quantification, and mapping of DNA modifications. Methods for deciphering DNA modifications have substantially improved over the last several years, which greatly revolutionize the field of DNA modifications. In addition to DNA cytosine methylation (5-methylcytosine, 5mC), the best-characterized epigenetic modification, many new modifications have been discovered to present in DNA in recent years.  <br/><br/>This book provides a comprehensive overview of available techniques and methods together with detailed step-by-step protocols for experimental procedures required to successfully perform analysis on various types of DNA modifications, including 5mC, 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), 5-carboxycytosine (5caC), 5-hydroxymethyluracil (5hmU), 5-formyluracil (5fU), N6-methyladenine (6mA), β-D-glucosyl-5-hydroxymethyluracil (base J) and 8-oxo-7,8-dihydroguanine (OG). This laboratory manual is a valuable source for biochemists and molecular biologists from different fields who wish to investigate DNA modifications.<br/><br/> 
<br/><br/><label>ISBN: </label>9781071612286 
<br/><br/><label>Subjects--Topical Terms: </label><br/>DNA modification  <br/>gene expression<br/> DNA Sequencing <br/>Mass spectrometry<br/>Detection Mapping
<br/><br/><label>Dewey Class. No.: </label>R572.8   / YUA-D