TY - BOOK AU - E J Corey AU - Barbara Czakó; László Kürti TI - Molecules and Medicine SN - 9780470260968 U1 - 615.1 COR-M PY - 2007/// CY - Hoboken, N.J. PB - John Wiley & Sons KW - Drugs. Molecules. Molecular biology. N1 - pt. I. Introduction -- Understanding structural diagrams of organic molecules -- Some common molecules -- Proteins and three-dimensional protein structure -- Some of the protein structures that appear in this book -- pt. II. Inflammatory, cardiovascular and metabolic diseases -- Anti-inflammatory agents -- Acetylsalicylic acid (Aspirin) -- Naproxen (Aleve) -- How do anti-inflammatory drugs work? -- Other eicosanoids in inflammation -- An overview of inflammation -- Celecoxib (Celebrex) -- Prednisone (Deltasone) -- Methotrexate (Trexall) -- Allopurinol (Zyloprim) -- Antiasthmatic and antiallergic agents -- Salmeterol (Serevent) -- Fluticasone propionate (Flovent) -- Montelukast sodium (Singulair) -- Tiotropium bromide (Spiriva) -- Loratadine (Claritin) -- Type 2 diabetes -- An overview of metabolic syndrome -- Antidiabetic and cholesterol-lowering agents -- Metformin (Glucophage) -- Glipizide (Glucotrol) -- Pioglitazone (Actos) -- Sitagliptin (Januvia) -- Atorvastatin (Lipitor) -- Ezetimibe (Zetia) -- Cardiovascular agents -- Atenolol (Tenormin) -- Enalapril (Vasotec) -- Candesartan cilexetil (Atacand) -- Aliskiren (Tekturna) -- Amlodipine (Norvasc) -- Nitroglycerin -- Clopidogrel bisulfate (Plavix) -- Digoxin (Lanoxin) -- Receptors and signaling -- Information flow into the cell by chemical signaling -- References for part II -- pt. III. Reproductive medicine -- Oral contraceptives -- Testosterone -- Mifepristone (Mifeprex) -- Oxytocin (Oxytocin) -- Sildenafil (Viagra) -- Osteoporosis -- Some aspects of osteoporosis -- Alendronate (Fosamax) -- Calcitriol (Rocaltrol) -- Raloxifene (Evista) -- Teriparatide (Forteo) -- Glaucoma and antiulcer agents -- Latanoprost (Xalatan) -- Ranitidine (Zantac) -- Omeprazole (Prilosec) -- References for part III. pt. IV. Autoimmune disease and organ transplant -- A brief survey of the immune system -- Immunosuppressive agents -- Azathioprine (Imuran) -- Mycophenolate mofetil (CellCept) -- Cyclosporin (Neoral) -- Tacrolimus (Prograf) -- FTY720 (Fingolimod) -- Infectious diseases -- Antibiotics -- Amoxicillin (Amoxil) -- Cefaclor (Ceclor) -- Doxycycline (Vibramycin) -- Azithromycin (Zithromax) -- Ciprofloxacin (Cipro) -- Trimethoprim (Triprim) -- Amikacin (Amikin) -- Vancomycin (Vancocin) -- Linezolid (Zyvox) -- Isoniazid (Laniazid) -- Ancillary antibiotics -- Drug resistance -- Antiviral agents -- On viruses and viral diseases -- Acyclovir (Zovirax) -- Ribavirin (Virazole) -- Oseltamivir (Tamiflu) -- Zidovudine (Retrovir, AZT) -- Zalcitabine (Hivid) -- Nevirapine (Viramune) -- Efavirenz (Sustiva) -- Lopinavir + ritonavir (Kaletra) -- UK427857 (Maraviroc) -- Antifungal agents -- Amphotericin (Fungizone) -- Fluconazole (Diflucan) -- Caspofungin (Cancidas) -- Terbinafine (Lamisil) -- Antimalarial and antiparasitic agents -- Parasitic diseases : a focus on malaria -- Chloroquine (Aralen) -- Artemether + lumefantrine (CoArtem) -- Atovaquone + proguanil (Malarone) -- Miltefosine (Impavido) -- Nitazoxanide (Alinia) -- Ivermectin (Stromectol) -- References for part IV. pt. V. Malignant disease -- An overview of cancer -- Capecitabine (Xeloda) -- Carboplatin (Paraplatin) -- Vinblastine (Velban) -- Paclitaxel (Taxol) -- Cyclophosphamide (Cytoxan) -- Tamoxifen (Nolvadex) -- Irinotecan (Camptosar) -- Bleomycin (Blenoxane) -- Imatinib (Gleevec) -- Sunitinib (Sutent) -- Bortezomib (Velcade) -- Ancillary anticancer agents -- References for part V -- pt. VI. Drugs acting on the nervous system -- Pain and analgesia -- Lidocaine (Xylocaine) -- Morphine (Avinza) -- Acetaminophen (Tylenol) -- Fentanyl (Duragesic) -- Sodium thiopental (Sodium Pentothal) -- Gabapentin (Neurontin) -- Diazepam (Valium) -- Sumatriptan (Imitrex) -- Hypnotics (insomnia) and antismoking -- Zolpidem (Ambien) -- Ramelteon (Rozerem) -- Varenicline (Chantix) -- The brain, neurotransmission and molecular neurotransmitters -- Neurodegenerative and psychiatric diseases -- Levodopa (Larodopa) -- Donepezil (Aricept) -- Antiepileptic agents -- Antianxiety agents -- Antidepressants -- Antipsychotics -- References for part VI -- Glossary -- Index N2 - Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas ER -