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Medicinal chemistry / Norma Dunlap, Donna M. Huryn.

By: Contributor(s): Material type: TextTextPublication details: New York: Garland Science, 2018.Description: xii, 495 pISBN:
  • 9780815345565
Subject(s): DDC classification:
  • 615.19 DUN-M
Contents:
Historical perspective and overview of drug discovery -- Drug discovery: hit and lead discovery -- Drug discovery: optimization of lead properties -- Medicinal chemistry strategies used in lead optimization -- The process of developing a drug from an optimized lead: -- Receptors as drug targets -- Enzymes as drug targets -- Protein-protein interactions and lipids as drug targets -- DNA and RNA as drug targets -- Anti-cancer drugs -- Infectious diseases I: antiviral and antifungal drugs -- Infectious diseases II: antibacterial and antiparasitic drugs -- Drugs acting on the CNS.
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Index.

Historical perspective and overview of drug discovery -- Drug discovery: hit and lead discovery -- Drug discovery: optimization of lead properties -- Medicinal chemistry strategies used in lead optimization -- The process of developing a drug from an optimized lead: -- Receptors as drug targets -- Enzymes as drug targets -- Protein-protein interactions and lipids as drug targets -- DNA and RNA as drug targets -- Anti-cancer drugs -- Infectious diseases I: antiviral and antifungal drugs -- Infectious diseases II: antibacterial and antiparasitic drugs -- Drugs acting on the CNS.

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