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Genome editing and engineering : from TALENs, ZFNs and CRISPRs to molecular surgery / edited by Krishnarao Appasani (GeneExpression Systems, Inc, Waltham, Massachusetts, USA), with a foreword by George M. Church (Harvard University Medical School, Boston, Massachusetts, USA).

Contributor(s): Material type: TextTextPublication details: UK; Cambridge University Press; 2018.Description: xxix, 472 pages, 32 unnumbered pages of plates : illustrations (some color)ISBN:
  • 9781107170377 (hardback)
  • 1107170370 (hardback)
Subject(s): DDC classification:
  • 576.507  APP.G
Summary: "Genome Editing and Engineering From Talens, ZFNs and CRISPRs to Molecular Surgery Recent advances in genome editing techniques using endonucleases such as TALENs and CRISPRs, combined with genomic engineering technologies have opened up a wide range of opportunities from applications in basic disease biology research to potential new diagnostic tools and clinical applications This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential application to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineer carry, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting"--
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Holdings
Item type Current library Home library Call number Status Date due Barcode
Book Book IUCEIB Library, University of Kerala General Stacks IUCEIB Library, University of Kerala 576.507 APP.G (Browse shelf(Opens below)) Available CEB911

Includes bibliographical references and index.

"Genome Editing and Engineering From Talens, ZFNs and CRISPRs to Molecular Surgery Recent advances in genome editing techniques using endonucleases such as TALENs and CRISPRs, combined with genomic engineering technologies have opened up a wide range of opportunities from applications in basic disease biology research to potential new diagnostic tools and clinical applications This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential application to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineer carry, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting"--

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