Amazon cover image
Image from Amazon.com
Image from Google Jackets
Image from OpenLibrary

Statistical issues in drug development / by Stephen Senn

By: Material type: TextTextPublication details: Chichester, England Hoboken, NJ : John Wiley & Sons, 2007.Edition: 2nd edDescription: xix, 498p. : illISBN:
  • 9780470018774 (cloth : alk. paper)
  • 0470018771 (cloth : alk. paper)
Subject(s): DDC classification:
  • 615/.190727 SEN
Online resources:
Contents:
A brief and superficial history of statistics for drug developers -- Design and interpretation of clinical trials as seen by a statistician -- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals -- The work of the pharmaceutical statistician -- Allocating treatments to patients in clinical trials -- Baselines and covariate information --
The measurement of treatment effects -- Demographic subgroups : representation and analysis -- Multiplicity -- Intention to treat, missing data and related matters -- One-sided and two-sided tests and other issues to do with significance and P-values -- Determining the sample size -- Multicentre trials -- Active control equivalence studies --
Meta-analysis -- Cross-over trials -- n-of-1 trials -- Sequential trials -- Dose-finding -- Concerning pharmacokinetics and pharmacodynamics -- Bioequivalence studies -- Safety data, harms, drug monitoring, and pharmaco-epidemiology -- Pharmaco-economics and portfolio management -- Concerning pharmacogenetics, pharmacogenomics, and related matters.
Tags from this library: No tags from this library for this title. Log in to add tags.
Holdings
Item type Current library Home library Call number Status Date due Barcode
Book Book Dept. of Statistics Processing Center Dept. of Statistics 615.190727 SEN (Browse shelf(Opens below)) Available STA9481

Includes bibliographical references and index.

A brief and superficial history of statistics for drug developers -- Design and interpretation of clinical trials as seen by a statistician -- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals -- The work of the pharmaceutical statistician -- Allocating treatments to patients in clinical trials -- Baselines and covariate information --

The measurement of treatment effects -- Demographic subgroups : representation and analysis -- Multiplicity -- Intention to treat, missing data and related matters -- One-sided and two-sided tests and other issues to do with significance and P-values -- Determining the sample size -- Multicentre trials -- Active control equivalence studies --

Meta-analysis -- Cross-over trials -- n-of-1 trials -- Sequential trials -- Dose-finding -- Concerning pharmacokinetics and pharmacodynamics -- Bioequivalence studies -- Safety data, harms, drug monitoring, and pharmaco-epidemiology -- Pharmaco-economics and portfolio management -- Concerning pharmacogenetics, pharmacogenomics, and related matters.

There are no comments on this title.

to post a comment.