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Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers

By: Contributor(s): Material type: TextTextPublication details: John Wiley & Sons 2016Description: 556 pISBN:
  • 9781119053330
Subject(s): DDC classification:
  • 615.902 DRU
Summary: As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. - Guides researchers as to what drug safety experiments are both practical and useful- Covers a variety of key topics - safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and -omics tools- Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods- Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices
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Item type Current library Home library Call number Status Date due Barcode
Book Book Dept. of Computational Biology and Bioinformatics Processing Center Dept. of Computational Biology and Bioinformatics 615.902 DRU (Browse shelf(Opens below)) Available DCB3026

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. - Guides researchers as to what drug safety experiments are both practical and useful- Covers a variety of key topics - safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and -omics tools- Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods- Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

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