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Epigentic technological applications

By: Material type: TextTextSeries: Translational epigenetics seriesPublication details: Elsevier/Academic Press 2015 AmsterdamDescription: xxiii, 491 p., 18 unnumbered pages of plates : ill (some color) ; 25 cmISBN:
  • 9780128010808
Subject(s): DDC classification:
  • 572.865 EPI
Contents:
1. The State of the Art of Epigenetic Technologies 2. Technologies for the Measurement and Mapping of Genomic 5-Methylcytosine and 5-Hydroxymethylcytosine 3. High-Throughput Sequencing-Based Mapping of Cytosine Modifications 4. Application of Mass Spectrometry in Translational Epigenetics 5. Techniques Analyzing Chromatin Modifications at Specific Single Loci 6. Comprehensive Analysis of Mammalian Linker-Histone Variants and Their Mutants 7. Crystallography-Based Mechanistic Insights into Epigenetic Regulation 8. Chemical and Genetic Approaches to Study Histone Modifications 9. Peptide Microarrays for Profiling of Epigenetic Targets 10. Current Methods for Methylome Profiling 11. Bioinformatics and Biostatistics in Mining Epigenetic Disease Markers and Targets 12. Computational Modeling to Elucidate Molecular Mechanisms of Epigenetic Memory 13. DNA Methyltransferase Inhibitors for Cancer Therapy 14. Histone Acetyltransferases: Enzymes, Assays, and Inhibitors 15. In Vitro Histone Deacetylase Activity Screening: Making a Case for Better Assays 16. Enzymatic Assays of Histone Methyltransferase Enzymes 17. Histone Methyltransferase Inhibitors for Cancer Therapy 18. Discovery of Histone Demethylase Inhibitors 19. Histone Demethylases: Background, Purification, and Detection 20. Animal Model Study of Epigenetic Inhibitors
Summary: Epigenetic Technological Applications is a compilation of state-of-the-art technologies involved in epigenetic research. Epigenetics is an exciting new field of biology research, and many technologies are invented and developed specifically for epigenetics study. With chapters covering the latest developments in crystallography, computational modeling, the uses of histones, and more, Epigenetic Technological Applications addresses the question of how these new ideas, procedures, and innovations can be applied to current epigenetics research, and how they can keep pushing discovery forward and beyond the epigenetic realm.
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Book Book Dept. of Computational Biology and Bioinformatics Processing Center Dept. of Computational Biology and Bioinformatics 572.865 EPI (Browse shelf(Opens below)) Available DCB2840

1. The State of the Art of Epigenetic Technologies 2. Technologies for the Measurement and Mapping of Genomic 5-Methylcytosine and 5-Hydroxymethylcytosine 3. High-Throughput Sequencing-Based Mapping of Cytosine Modifications 4. Application of Mass Spectrometry in Translational Epigenetics 5. Techniques Analyzing Chromatin Modifications at Specific Single Loci 6. Comprehensive Analysis of Mammalian Linker-Histone Variants and Their Mutants 7. Crystallography-Based Mechanistic Insights into Epigenetic Regulation 8. Chemical and Genetic Approaches to Study Histone Modifications 9. Peptide Microarrays for Profiling of Epigenetic Targets 10. Current Methods for Methylome Profiling 11. Bioinformatics and Biostatistics in Mining Epigenetic Disease Markers and Targets 12. Computational Modeling to Elucidate Molecular Mechanisms of Epigenetic Memory 13. DNA Methyltransferase Inhibitors for Cancer Therapy 14. Histone Acetyltransferases: Enzymes, Assays, and Inhibitors 15. In Vitro Histone Deacetylase Activity Screening: Making a Case for Better Assays 16. Enzymatic Assays of Histone Methyltransferase Enzymes 17. Histone Methyltransferase Inhibitors for Cancer Therapy 18. Discovery of Histone Demethylase Inhibitors 19. Histone Demethylases: Background, Purification, and Detection 20. Animal Model Study of Epigenetic Inhibitors

Epigenetic Technological Applications is a compilation of state-of-the-art technologies involved in epigenetic research. Epigenetics is an exciting new field of biology research, and many technologies are invented and developed specifically for epigenetics study. With chapters covering the latest developments in crystallography, computational modeling, the uses of histones, and more, Epigenetic Technological Applications addresses the question of how these new ideas, procedures, and innovations can be applied to current epigenetics research, and how they can keep pushing discovery forward and beyond the epigenetic realm.

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