Section I. Fundamental principles of pharmacology -- Drug-receptor interactions / Zachary S. Morris and David E. Golan -- Pharmacodynamics / Quentin J. Baca and David E Golan -- Pharmacokinetics / Quentin J. Baca and David E. Golan -- Drug metabolism / Cullen Taniguchi and F. Peter Guengerich -- Drug toxicity / Michael W. Conner [and others] -- Pharmacogenomics / Liewei Wang and Richard M. Weinshilboum. Section II. Principles of neuropharmacology -- Section IIA. Fundamental principles of neuropharmacology -- Principles of cellular excitability and electrochemical transmission / Lauren K. Buhl, John Dekker, and Gary R. Strichartz -- Principles of nervous system physiology and pharmacology / Joshua M. Galanter, Susannah B. Comes, and Daniel H. Lowenstein -- Section IIB. Principles of autonomic and peripheral nervous system pharmacology -- Cholinergic pharmacology / Alireza Atri, Michael S. Chang, and Gary R. Strichartz -- Adrenergic pharmacology / Brian B. Hoffman and Freddie M. Williams -- Local anesthetic pharmacology / Joshua M. Schulman and Gary R. Strichartz -- Section IIC. Principles of central nervous system pharmacology -- Pharmacology of GABAergic and glutamatergic neurotransmission / Stuart A. Forman [and others] -- Pharmacology of dopaminergic neurotransmission / David G. Standaert and Ryan R. Walsh -- Pharmacology of serotonergic and central adrenergic neurotransmission / Miles Berger and Bryan Roth -- Pharmacology of abnormal electrical neurotransmission in the central nervous system / Susannah B. Comes, Edmund A. Griffin, Jr., and Daniel H. Lowenstein -- General anesthetic pharmacology / Jacob Wouden and Keith W. Miller -- Pharmacology of analgesia / Robert S. Griffin and Clifford J. Woolf -- Pharmacology of drugs of abuse / Peter R. Martin, Sachin Patel, and Robert M. Swift. Section III. Principles of cardiovascular pharmacology -- Pharmacology of cholesterol and lipoprotein metabolism / David E. Cohen and Ehrin J. Armstrong -- Pharmacology of volume regulation / Mallar Bhattacharya and Seth L. Alper -- Pharmacology of vascular tone / Deborah Yeh Chong and Thomas Michel -- Pharmacology of hemostasis and thrombosis / April W. Armstrong and David E. Golan -- Pharmacology of cardiac rhythm / Ehrin J. Armstrong, April W. Armstrong, and David E. Clapham -- Pharmacology of cardiac contractility / Ehrin J. Armstrong and Thomas P. Rocco -- Integrative cardiovascular pharmacology: Hypertension, ischemic heart disease, and heart failure / Ehrin J. Armstrong, April W. Armstrong, and Thomas P. Rocco. Section IV. Principles of endocrine pharmacology -- Pharmacology of the hypothalamus and pituitary gland / Anand Vaidya and Ursula B. Kaiser -- Pharmacology of the thyroid gland / Ehrin J. Armstrong, Armen H. Tashjian, and William W. Chin -- Pharmacology of the adrenal cortex / Rajesh Garg and Gail K. Adler -- Pharmacology of reproduction / Ehrin J. Armstrong and Robert L. Barbieri -- Pharmacology of the endocrine pancreas and glucose homeostasis / Aimee D. Shu and Steven E. Shoelson -- Pharmacology of bone mineral homeostasis / Robert M. Neer, Ehrin J. Armstrong, and Armen H. Tashjian, Jr. Section V. Principles of chemotherapy -- Principles of antimicrobial and antineoplastic pharmacology / Quentin J. Baca, Donald M. Coen, and David E. Golan -- Pharmacology of bacterial infections: DNA replication, transcription, and translation / Marvin Ryou and Donald M. Coen -- Pharmacology of bacterial and mycobacterial infections: Cell wall synthesis / Tania Lupoli [and others] -- Pharmacology of fungal infections / Ali Alikhan, Charles R. Taylor, and April W. Armstrong -- Pharmacology of parasitic infections / Louise C. Ivers and Edward T. Ryan -- Pharmacology of viral infedctions / Robert W. Yeh and Donald M. Coen -- Pharmacology of cancer: Genome synthesis, stability, and maintenance / David A. Barbie and David A. Frank -- Pharmacology of cancer: Signal transduction / David A. Barbie and David A. Frank -- Principles of combination chemotherapy / Quentin J. Baca, Donald M. Coen, and David E. Golan. Section VI. Principles of inflammation and immune pharmacology -- Principles of inflammation and the immune system / Ehrin J. Armstrong and Lloyd B. Klickstein -- Pharmacology of eicosanoids / David M. Dudzinski and Charles N. Serhan -- Histamine pharmacology / Cindy Chambers, Joseph C. Kvedar, and April W. Armstrong -- Pharmacology of hematopoiesis and immunomodulation / Andrew J. Wagner, Ramy A. Arnaout, and George D. Demetri -- Pharmacology of immunosuppression / April W. Armstrong, Ehrin J. Armstrong, and Lloyd B. Klickstein -- Integrative inflammation pharmacology: Peptic ulcer disease / Dalia S. Nagel and Helen M. Shields -- Integrative inflammation pharmacology: Asthma / Joshua M. Galanter and Stephen Lazarus -- Integrative inflammation pharmacology: Gout / Ehrin J. Armstrong and Lloyd B. Klickstein. Section VII. Fundamentals of drug development and regulation -- Drug discovery and preclinical development / John L. Vahle [and others] -- Clinical drug evaluation and regulatory approval / Mark A. Goldberg, Alexander E. Kuta, and John L. Vahle -- Systematic detection of adverse drug events / Jerry Avom. Section VIII. Environmental toxicology -- Environmental toxicology / Laura C. Green ... [et al. Section IX. Frontiers in pharmacology -- Protein therapeutics / Quentin J. Baca, Benjamin Leader, and David E. Golan -- Drug delivery modalities / Joshua D. Moss and Robert S. Langer.

The Pathophysiologic Basis of Drug Therapy, Third Edition, serves as the primary textbook for a first course in pharmacology. It offers an integrated mechanism and systems-based approach that incorporates the cell biology, biochemistry, physiology, and pathophysiology of organ systems. The completely updated Third Edition reflects current research findings and features more than 400 full-color illustrations and Drug Summary Tables.