Nucleic acid sequence and structure databases / Stefan Washietl and Ivo L. Hofacker -- Genomic databases and resources at the National Center for Biotechnology Information / Tatiana Tatusova -- Protein sequence databases / Michael Rebhan -- Protein structure databases / Roman A. Laskowski -- Protein domain architectures / Nicola J. Mulder -- Thermodynamic database for proteins : features and applications / M. Michael Gromiha and Akinori Sarai -- Enzyme databases / Dietmar Schomburg and Ida Schomburg -- Biomolecular pathway databases / Hong Sain Ooi [and others] -- Databases of protein-protein interactions and complexes / Hong Sain Ooi [and others] -- Proximity measures for cluster analysis / Oliviero Carugo -- Clustering criteria and algorithms / Oliviero Carugo -- Neural networks / Zheng Rong Yang -- A user's guide to support vector machines / Asa Ben-Hur and Jason Weston -- Hidden Markov models in biology / Claus Vogl and Andreas Futschik -- Integrated tools for biomolecular sequence-based function prediction as exemplified by the ANNOTATOR software environment / Georg Schneider [and others] -- Computational methods for ab initio and comparative gene finding / Ernesto Picardi and Graziano Pesole -- Sequence and structure analysis of noncoding RNAs / Stefan Washietl -- Conformational disorder / Sonia Longhi, Philippe Lieutaud, and Bruno Canard -- Protein secondary structure prediction / Walter Pirovano and Jaap Heringa -- Analysis and prediction of protein quaternary structure / Anne Poupon and Joel Janin -- Prediction of posttranslational modification of proteins from their amino acid sequence / Birgit Eisenhaber and Frank Eisenhaber -- Protein crystallizability / Pawel Smialowski and Dmitrij Frishman.

In this book, experts in the field contribute valuable information about the sources of information and the techniques used for "mining" new insights out of databases. The book covers a wide range of biological systems and in silico approaches.