he first look at a genome : sequence statistics -- All the sequence's men : gene finding -- All in the family : sequence alignment -- The boulevard of broken genes : hidden Markov methods -- Are Neanderthals among us? : variation within and between species -- Fighting HIV : natural selection at the molecular level -- SARS : a post-genomic epidemic : phylogenetic analysis -- Welcome to the hotel Chlamydia : whole genome comparisons -- The genomics of wine-making : analysis of gene expression -- A bed-time story : identification of regulatory sequences.

Are we related to Neanderthals? Where did SARS come from? Which part of our genome is evolving the fastest? These are some of the questions that can be answered by statistical and computational analysis of genetic data. This text presents an introduction to computational genomics.