Computational methods for protein structure prediction / I.A. Cymerman [and others] -- "Meta" approaches to protein structure prediction / J.M. Bujnicki, D. Fischer -- From molecular modeling to drug design / M. Cohen-Gonsaud [and others] -- Structure determination of macromolecular complexes by experiment and computation / F. Alber, N. Eswar, A. Sali -- Modeling protein folding pathways / C. Bystroff, Y. Shao -- Structural bioinformatics and NMR structure determination / J.P. Linge, M. Nilges -- Bioinformatics-guided identification and experimental characterization of novel RNA methytransferases / J.M. Bujnicki [and others] -- Finding missing tRNA modification genes: a comparative genomics goldmine / V. de Crécy-Lagard -- Evolution and function of processosome, the complex that assembles ribosomes in eukaryotes: clues from comparative sequence analysis / A. Mushegian -- Bioinformatics-guided experimental characterization of mismatch-repair enzymes and their relatives / P. Friedhoff -- Predicting functional residues in DNA glycosylases by analysis of structure and conservation / D.O. Zharkov.

Presents applications of bioinformatics tools that experimental research scientists use in daily practice. This book reviews computational methods for protein sequence-structure-function analysis, followed by methods that use experimental data obtained in the laboratory to improve functional predictions