Evolutionary genomics leads the way / David Penny & Lesley J. Collins -- Current approaches to phylogenomic reconstruction / Denis Baurain & Hervé Philippe -- The universal tree of life and the Last Universal Cellular Ancestor : revolution and counterrevolutions / Patrick Forterre -- Eukaryotic evolution : the importance of the stem group / Anthony M. Poole -- The role of information in evolutionary genomics of bacteria / Antoine Danchin & Agnieszka Sekowska -- Evolutionary genomics of yeasts / Bernard Dujon -- Genotypes and phenotypes in the evolution of molecules / Peter Schuster -- Genome evolution studied through protein structure / Philip E. Bourne [and others] -- Chromosomal rearrangements in evolution / Hao Zhao & Guillaume Bourque -- Molecular structure and evolution of genomes / Todd A. Castoe, A.P. Jason de Koning, & David D. Pollock -- The evolution of protein material costs / Jason G. Bragg & Andreas Wagner -- Protein domains as evolutionary units / Andrew D. Moore & Erich Bornberg-Bauer -- Domain family analyses to understand protein function evolution / Adam James Reid [and others] -- Noncoding RNA / Alexander Donath [and others] -- Evolutionary genomics of microRNAs and their relatives / Andrea Tanzer [and others] -- Phylogenetic utility of RNA structure : evolution's arrow and emergence of early biochemistry and diversified life / Feng-Jie Sun, Ajith Harish, & Gustavo Caetano-Anollés -- A hitchhiker's guide to evolving networks / Charles G. Kurland & Otto G. Berg -- Evolution of metabolic networks / Eivind Almaas -- Single-gene and whole-genome duplications and the evolution of protein-protein interaction networks / Grigoris Amoutzias & Yves Van de Peer -- Modularity and dissipation in evolution of macromolecular structures, functions, and networks / Gustavo Caetano-Anollés, Liudmila Yafremava, & Jay E. Mittenthal.

A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagramsâ€ââ,¬Âmacromolecular components in interactionâ€ââ,¬Âin the context of genomic complements. The book also features: ÂÃ,· A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology ÂÃ,· A special section on RNA biologyâ€ââ,¬Âtranslation, evolution of structure, and micro RNA and regulation of gene expression ÂÃ,· Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease ÂÃ,· Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.