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DNA recombination : a subject collection from Cold Spring Harbor perspectives in biology / edited by Stephen Kowalczykowski, University of California, Davis, Neil Hunter, University of California, Davis and Wolf-Dietrich Heyer, University of California, Davis.

Contributor(s): Material type: TextTextPublication details: Cold Spring Harbor, N.Y Cold Spring Harbor Laboratory Press. : 2016.Description: viii, 549 pages : illustrations (chiefly color)ISBN:
  • 9781621820093 (hardback)
  • 1621820092 (hardback)
Subject(s): DDC classification:
  • 572.8/77 KOW
Contents:
Machine generated contents note: -- (preliminary) -- 1. Overview of RM: Stephen Kowalczykowski -- 1.1. Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair -- Anuja Mehta and James E. Haber -- 1.2. End Resection at DNA Double-Strand Breaks: Mechanism and Regulation -- Lorraine S. Symington -- 1.3. DNA Pairing and Annealing: Processes in Homologous Recombination and Homology-Directed Repair Scott W. Morrical -- 1.4. Mediators of Homologous DNA Pairing -- Alex Zelensky, Roland Kanaar, and Claire Wyman -- 1.5. Regulation of DNA pairing in Homologous Recombination -- James M. Daley, William A. Gaines, YoungHo Kwon, and Patrick Sung -- 1.6. The Dissolution of Double Holliday Junctions -- Anna H. Bizard and Ian D. Hickson -- 1.7. Holliday Junction Resolvases -- Haley D.M. Wyatt and Stephen C. West -- 1.8. Structural Studies of DNA End Detection and Resection in Homologous Recombination -- Christian Bernd Schiller, Florian Ulrich Seifert, Christian Linke-Winnebeck, and Karl-Peter Hopfner -- 2. Regulation of recombination: Wolf-Dietrich Heyer -- 2.1. Cell cycle and DDR-mediated regulation homologous recombination -- John Petrini -- 2.2. Histone modifications & chromatin remodelling: Alain Nicolas -- 2.3. Cell Biology of Mitotic Recombination -- Michael Lisby and Rodney Rothstein -- 2.4. Transcription and Recombination: When RNA Meets DNA -- Andrés Aguilera and Hélène Gaillard -- 2.5. Replication and Recombination -- Aisha H. Syeda, Michelle Hawkins, and Peter McGlynn -- 2.6. Mismatch Repair During Homologous and Homeologous Recombination -- Maria Spies and Richard Fishel -- 2.7. The Role of DSB Repair Pathways at Functional and Dysfunctional Telomeres -- Ylli Doksani and Titia de Lange -- 2.8. Gross chromosomal rearrangementsEL: Richard Kolodner -- 2.9. Mechanisms of Gene Duplication and Amplification -- Andrew B. Reams and John R. Roth -- 2.10. Recombinational DNA Repair and Human Disease: BRCA1, BRCA2, and Associated Proteins -- Rohit Prakash, Yu Zhang, Weiran Feng, and Maria Jasin -- 3. Meitoic recombination--Overview: Neil Hunter -- 3.1. Recombination, Pairing, and Synapsis of Homologs During Meiosis -- Denise Zickler and Nancy Kleckner -- 3.2. Mechanism and Regulation of Meiotic Recombination Initiation -- Isabel Lam and Scott Keeney -- 3.3. DNA Strand Exchange and RecA Homologs in Meiosis -- M. Scott Brown and Douglas K. Bishop -- 3.4. Control of crossover formation -- Michael Lichten -- 3.5. The Meiotic Checkpoint Network: Step-by-Step Through Meiotic Prophase -- Vijayalakshmi V. Subramanian and Andreas Hochwagen -- 3.6. Human Aneuploidy, Infertility, and the Maternal Age Effect -- Mary Herbert, Dimitrios.
Summary: "Recombination mechanisms allow cells to break and reattach DNA sequences. They are important for repair of damaged DNA. They also help generate additional genetic diversity in sperm and eggs cells by mixing DNA sequences from maternal and paternal chromosomes. This volume explores the molecular details of recombination and their roles in genome maintenance and meiosis"--
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Holdings
Item type Current library Home library Call number Status Date due Barcode
Book Book Dept. of Bio-Technology General Stacks Dept. of Bio-Technology 572.877 KOW (Browse shelf(Opens below)) Available BTY2710
Book Book IUCEIB Library, University of Kerala General Stacks IUCEIB Library, University of Kerala 572.877 KOW.D (Browse shelf(Opens below)) Available CEB227

Includes bibliographical references and index.

Machine generated contents note: -- (preliminary) -- 1. Overview of RM: Stephen Kowalczykowski -- 1.1. Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair -- Anuja Mehta and James E. Haber -- 1.2. End Resection at DNA Double-Strand Breaks: Mechanism and Regulation -- Lorraine S. Symington -- 1.3. DNA Pairing and Annealing: Processes in Homologous Recombination and Homology-Directed Repair Scott W. Morrical -- 1.4. Mediators of Homologous DNA Pairing -- Alex Zelensky, Roland Kanaar, and Claire Wyman -- 1.5. Regulation of DNA pairing in Homologous Recombination -- James M. Daley, William A. Gaines, YoungHo Kwon, and Patrick Sung -- 1.6. The Dissolution of Double Holliday Junctions -- Anna H. Bizard and Ian D. Hickson -- 1.7. Holliday Junction Resolvases -- Haley D.M. Wyatt and Stephen C. West -- 1.8. Structural Studies of DNA End Detection and Resection in Homologous Recombination -- Christian Bernd Schiller, Florian Ulrich Seifert, Christian Linke-Winnebeck, and Karl-Peter Hopfner -- 2. Regulation of recombination: Wolf-Dietrich Heyer -- 2.1. Cell cycle and DDR-mediated regulation homologous recombination -- John Petrini -- 2.2. Histone modifications & chromatin remodelling: Alain Nicolas -- 2.3. Cell Biology of Mitotic Recombination -- Michael Lisby and Rodney Rothstein -- 2.4. Transcription and Recombination: When RNA Meets DNA -- Andrés Aguilera and Hélène Gaillard -- 2.5. Replication and Recombination -- Aisha H. Syeda, Michelle Hawkins, and Peter McGlynn -- 2.6. Mismatch Repair During Homologous and Homeologous Recombination -- Maria Spies and Richard Fishel -- 2.7. The Role of DSB Repair Pathways at Functional and Dysfunctional Telomeres -- Ylli Doksani and Titia de Lange -- 2.8. Gross chromosomal rearrangementsEL: Richard Kolodner -- 2.9. Mechanisms of Gene Duplication and Amplification -- Andrew B. Reams and John R. Roth -- 2.10. Recombinational DNA Repair and Human Disease: BRCA1, BRCA2, and Associated Proteins -- Rohit Prakash, Yu Zhang, Weiran Feng, and Maria Jasin -- 3. Meitoic recombination--Overview: Neil Hunter -- 3.1. Recombination, Pairing, and Synapsis of Homologs During Meiosis -- Denise Zickler and Nancy Kleckner -- 3.2. Mechanism and Regulation of Meiotic Recombination Initiation -- Isabel Lam and Scott Keeney -- 3.3. DNA Strand Exchange and RecA Homologs in Meiosis -- M. Scott Brown and Douglas K. Bishop -- 3.4. Control of crossover formation -- Michael Lichten -- 3.5. The Meiotic Checkpoint Network: Step-by-Step Through Meiotic Prophase -- Vijayalakshmi V. Subramanian and Andreas Hochwagen -- 3.6. Human Aneuploidy, Infertility, and the Maternal Age Effect -- Mary Herbert, Dimitrios.

"Recombination mechanisms allow cells to break and reattach DNA sequences. They are important for repair of damaged DNA. They also help generate additional genetic diversity in sperm and eggs cells by mixing DNA sequences from maternal and paternal chromosomes. This volume explores the molecular details of recombination and their roles in genome maintenance and meiosis"--

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