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Type 1 diabetes : a subject collection from Cold Spring Harbor perspectives in medicine / edited by Jeffrey A. Bluestone, Mark A. Atkinson, Peter Arvan.

Contributor(s): Material type: TextTextPublication details: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, c2012.Description: xi, 305 p. : ill. (some col.), col. mapsISBN:
  • 9781936113217 (hardcover : alk. paper)
  • 193611321X (hardcover : alk. paper)
Other title:
  • Type one diabetes
Subject(s): DDC classification:
  • 616.4/622 BLU
Contents:
The pathogenesis and natural history of type 1 diabetes / Mark A. Atkinson -- Islet autoantigens : structure, function, localization, and regulation / Peter Arvan ... [et al.] -- Endoplasmic reticulum stress, pancreatic B-cell degeneration, and diabetes / Feroz R. Papa -- Generating beta-cells from stem cells//the story so far / Matthias Hebrok -- Virus infections in type 1 diabetes / Ken T. Coppieters, Tobias Boettler, and Matthias von Herrath -- Environmental triggers of type 1 diabetes / Mikael Knip and Olli Simell -- Immunologic and metabolic biomarkers of B-cell destruction in the diagnosis of T1D / Jasmin Lebastchi and Kevan C. Herold -- Clinical interventions for the treatment of T1D / Lucienne Chatenoud, Katharina Warncke, and Annette-G. Ziegler -- Connecting type 1 and type 2 diabetes through innate immunity / Justin I. Odegaard and Ajay Chawla --
Genetics of type 1 diabetes / Janelle A. Noble and Henry A. Erlich -- Humoral autoimmunity and the prediction of type-1 diabetes / Massimo Pietropaolo, Roberto Towns, and George S. Eisenbarth -- Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice / Michael A. Brehm, Alvin C. Powers, Leonard D. Shultz, and Dale L. Greiner -- Do MHCII-presented neo-antigens drive type-1 diabetes and other autoimmune diseases? / Philippa Marrack and John W. Kappler -- Antigen-specific therapeutic approaches in type 1 diabetes / Xavier Clement-Casares ... [et al.] -- Antigen targets of type 1 diabetes autoimmunity / Bart O. Roep and Mark Peakman -- The hygiene hypothesis : an explanation for the increased frequency of insulin-dependent diabetes / Jean-François Bach and Lucienne Chatenoud -- Breakdown in peripheral tolerance in type 1 diabetes in mice and humans / Lukas T. Jeker, Hélène Bour-Jordan, and Jeffrey A. Bluestone -- Update on islet transplantation / Michael McCall and A. M. James Shapiro.
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"A subject collection from Cold Spring Harbor perspectives in medicine"-- T.p. verso.

Includes bibliographical references and index.

The pathogenesis and natural history of type 1 diabetes / Mark A. Atkinson -- Islet autoantigens : structure, function, localization, and regulation / Peter Arvan ... [et al.] -- Endoplasmic reticulum stress, pancreatic B-cell degeneration, and diabetes / Feroz R. Papa -- Generating beta-cells from stem cells//the story so far / Matthias Hebrok -- Virus infections in type 1 diabetes / Ken T. Coppieters, Tobias Boettler, and Matthias von Herrath -- Environmental triggers of type 1 diabetes / Mikael Knip and Olli Simell -- Immunologic and metabolic biomarkers of B-cell destruction in the diagnosis of T1D / Jasmin Lebastchi and Kevan C. Herold -- Clinical interventions for the treatment of T1D / Lucienne Chatenoud, Katharina Warncke, and Annette-G. Ziegler -- Connecting type 1 and type 2 diabetes through innate immunity / Justin I. Odegaard and Ajay Chawla --

Genetics of type 1 diabetes / Janelle A. Noble and Henry A. Erlich -- Humoral autoimmunity and the prediction of type-1 diabetes / Massimo Pietropaolo, Roberto Towns, and George S. Eisenbarth -- Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice / Michael A. Brehm, Alvin C. Powers, Leonard D. Shultz, and Dale L. Greiner -- Do MHCII-presented neo-antigens drive type-1 diabetes and other autoimmune diseases? / Philippa Marrack and John W. Kappler -- Antigen-specific therapeutic approaches in type 1 diabetes / Xavier Clement-Casares ... [et al.] -- Antigen targets of type 1 diabetes autoimmunity / Bart O. Roep and Mark Peakman -- The hygiene hypothesis : an explanation for the increased frequency of insulin-dependent diabetes / Jean-François Bach and Lucienne Chatenoud -- Breakdown in peripheral tolerance in type 1 diabetes in mice and humans / Lukas T. Jeker, Hélène Bour-Jordan, and Jeffrey A. Bluestone -- Update on islet transplantation / Michael McCall and A. M. James Shapiro.

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