MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03053cam a22003378i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
18828639 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20220107153026.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
151022s2016 enk b 001 0 eng |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780521768009 (hardback) |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(DNLM)101670855 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
DNLM/DLC |
| Transcribing agency |
DLC |
| Description conventions |
rda |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
pcc |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RS420 |
| 060 10 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
|---|
| Classification number |
QV 745 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
615.1/9 |
| Edition number |
23 |
| Item number |
LOG-B |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Loging, William T. |
| Relator term |
editor. |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Bioinformatics and computational biology in drug discovery and development / |
| Statement of responsibility, etc. |
edited by William T. Loging. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
1st ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cambridge, United Kingdom : |
| Name of publisher, distributor, etc. |
Cambridge University Press, |
| Date of publication, distribution, etc. |
c2016. |
| 263 ## - PROJECTED PUBLICATION DATE |
|---|
| Projected publication date |
1601 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
xi,233p.: |
| Dimensions |
cm. |
| Other physical details |
25 cm. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes bibliographical references and index. |
| 505 8# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Machine generated contents note: Foreword; Preface: the future of drug discovery and health care / Eric Schadt; 1. The art and science of the Drug Discovery Pipeline (DDP) / William T. Loging; 2. Computational approaches to drug target identification / Thomas B. Freeman and Pek Lum; 3. Understanding human disease knowledge through text mining / Raul Rodriguez-Esteban; 4. Integrating translational biomarkers into drug development / Jonathan Phillips; 5. Computational phenotypic assessment of small molecules in drug discovery / William T. Loging and Thomas B. Freeman; 6. Data visualization and the DDP process / Ke Xu; 7. Information visualization - important IT considerations / Telmo Silva; 8. The New Drug Application (NDA) and regulatory approval stages / William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield; 9. Clinical trial failures and drug repositioning / Mark Crawford and Jeff Handler; Appendix I. Additional knowledge-based analysis approaches / Raul Rodriguez-Esteban; Appendix II. Open source tools and public data sources / Yirong Wang and William T. Loging; Index. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
"Computational biology drives discovery through its use of high-throughput informatics approaches. This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through the use of previously unpublished, real-life case studies the impact of a range of computational approaches are discussed at various phases of the pipeline. Additionally, a focus section provides innovative visualisation approaches, from both the drug discovery process as well as from other fields that utilise large datasets, recognising the increasing use of such technology. Serving the needs of early career and more experienced scientists, this up-to-date reference provides an essential introduction to the process and background of drug discovery, highlighting how computational researchers can contribute to that pipeline"--Provided by publisher. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Drug Discovery |
| General subdivision |
methods. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biomarkers, Pharmacological. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Computational Biology |
| General subdivision |
methods. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Data Mining |
| General subdivision |
methods. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Book |
