An Introduction to Medicinal Chemistry (Record no. 296180)

MARC details
000 -LEADER
fixed length control field 03158nam a22001697a 4500
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780199697397
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615.19 PAT-I
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Graham L. Patrick
245 ## - TITLE STATEMENT
Title An Introduction to Medicinal Chemistry
250 ## - EDITION STATEMENT
Edition statement 5th ed
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Oxford University Press
Date of publication, distribution, etc. 2013
Place of publication, distribution, etc. Oxford
300 ## - PHYSICAL DESCRIPTION
Extent xxiii, 789 p. : ill (some color) ; 25 cm
505 ## - FORMATTED CONTENTS NOTE
Formatted contents note Drugs and drug targets -- an overview -- Drug targets : structure and function -- Protein structure and function -- Enzymes: structure and function -- Receptors: structure and function -- Receptors and signal transduction -- Nucleic acids: structure and function -- Pharmacodynamics and pharmacokinetics -- Enzymes as drug targets -- Receptors as drug targets -- Nucleic acids as drug targets -- Miscellaneous drug targets -- Pharmacokinetics and related topics -- Statins -- Drug discovery, design, and development -- Drug discovery: finding a lead -- Drug design: optimizing target interactions -- Drug design: optimizing access to the target -- Getting the drug to market -- The design of ACE inhibitors -- Artemisinin and related antimalarial drugs -- The design of oxamniquine -- Tools of the trade -- Combinatorial synthesis -- Computers in medicinal chemistry -- Quantitative structure-activity relationships (QSAR) -- De novo design of a thymidylate synthase inhibitor -- Selected topics in medicinal chemistry -- Antibacterial agents -- Antiviral agents -- Anticancer agents -- Cholinergics, anticholinergics, and anticholinesterases -- Drugs acting on the adrenergic nervous system -- Opioid analgesics -- Antiulcer agents -- Steroidal anti-inflammatory agents -- Design of a novel antidepressant.
520 ## - SUMMARY, ETC.
Summary, etc. An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful 'tools of the trade'. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents. Learning features throughout An Introduction to Medicinal Chemistry help to unlock this fascinating subject. A glossary helps to familiarise the language of medicinal chemistry. Boxes present in-depth material and explore how concepts are applied in practice. Key points summarise sections within chapters, providing a basis for revision, and questions at the end of chapters and on the accompanying Online Resource Centre allow the reader to test their understanding and develop molecular modelling skills.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pharmaceutical chemistry. Chemistry, Pharmaceutical. Drug Design.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Book
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Total Renewals Full call number Barcode Checked out Date last seen Date last checked out Price effective from Koha item type
        Dept. of Computational Biology and Bioinformatics Dept. of Computational Biology and Bioinformatics Processing Center 04/04/2016 3 2 615.19 PAT-I DCB2949 18/04/2022 18/01/2022 18/01/2022 19/07/2019 Book