Dynamic Systems Biology Modeling and Simulation (Record no. 295699)

MARC details
000 -LEADER
fixed length control field 02547nam a2200157Ia 4500
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 978-0124104112
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 570.113 DIS-D
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Joseph J DiStefano, III
245 ## - TITLE STATEMENT
Title Dynamic Systems Biology Modeling and Simulation
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Amsterdam
Name of publisher, distributor, etc. Elsevier, Academic Press
Date of publication, distribution, etc. 2013
300 ## - PHYSICAL DESCRIPTION
Extent xxii, 859 pages : illustrations (chiefly color) ; 28 cm
505 ## - FORMATTED CONTENTS NOTE
Formatted contents note Biosystem modeling and simulation : nomenclature and philosophy -- Math models of systems : biomodeling 101 -- Computer simulation methods -- Structural biomodeling from theory and data : compartmentalizations -- Structural biomodeling from theory and data : sizing, distinguishing and simplifying multicompartmental models -- Nonlinear mass action and biochemical kinetic interaction modeling -- Cellular systems biology modeling : deterministic and stochastic -- Physiologically based, whole-organism kinetics and noncompartmental modeling -- Biosystem stability and oscillations -- Structural identifiability -- Parameter sensitivity methods -- Parameter estimation and numerical identifiability -- Parameter estimation methods II : facilitating, simplifying and working with data -- Biocontrol system modeling, simulation, and analysis -- Data-driven modeling and alternative hypothesis testing -- Experiment design and optimization -- Model reduction and network inference in dynamic systems biology.
520 ## - SUMMARY, ETC.
Summary, etc. Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems - from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial - with clearly spelled-out and unified nomenclature - derived from the author\\\'s own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Systems biology. Systems biology -- Mathematical models. Biological systems -- Computer simulation.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Book
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection code Home library Current library Shelving location Date acquired Full call number Barcode Date last seen Price effective from Koha item type Public note
    Dewey Decimal Classification     Reference Dept. of Computational Biology and Bioinformatics Dept. of Computational Biology and Bioinformatics Reference 01/09/2015 570.113 DIS-D DCB2537 01/09/2015 19/07/2019 Book REFERENCE COLLECTIONS