Statistical Theory and Methods for Evolutionary Genomics (Record no. 295181)

MARC details
000 -LEADER
fixed length control field 02247nam a2200169Ia 4500
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780199213269
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572.838 GU-S
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Xun Gu
245 ## - TITLE STATEMENT
Title Statistical Theory and Methods for Evolutionary Genomics
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Oxford ; New York
Name of publisher, distributor, etc. Oxford University Press
Date of publication, distribution, etc. 2011
300 ## - PHYSICAL DESCRIPTION
Extent xi, 259 p. : ill ; 26 cm.
490 ## - SERIES STATEMENT
Series statement Oxford biology.
505 ## - FORMATTED CONTENTS NOTE
Formatted contents note 1. Basics in molecular evolution -- 2. Basics in bioinformatics and statistics -- 3. Functional divergence after gene duplication: statistical modeling -- 4. Functional divergence after gene duplication: applications and others -- 5. Phylogenomic expression analysis between duplicate genes -- 6. Expression between duplicate genes: genome-wide analysis -- 7. Tissue-driven hypothesis of genomic evolution -- 8. Gene pleiotropy and evolution of protein sequence -- 9. Modeling the genomic evolution of gene contents -- 10. Advanced topics in systems biology and network evolution.
520 ## - SUMMARY, ETC.
Summary, etc. "Evolutionary genomics is a relatively new research field with the ultimate goal of understanding the underlying evolutionary and genetic mechanisms for the emergence of genome complexity under changing environments. It stems from an integration of high throughput data from functional genomics, statistical modelling and bioinformatics, and the procedure of phylogeny-based analysis. Statistical Theory and Methods for Evolutionary Genomics summarises the statistical framework of evolutionary genomics, and illustrates how statistical modelling and testing can enhance our understanding of functional genomic evolution. The book reviews the recent developments in methodology from an evolutionary perspective of genome function, and incorporates substantial examples from high throughput data in model organisms. In addition to phylogeny-based functional analysis of DNA sequences, the author includes extensive discussion on how new types of functional genomic data (e.g. microarray) can provide exciting new insights into the evolution of genome function, which can lead in turn to an understanding of the emergence of genome complexity during evolution"-
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Genomics -Statistical methods. Evolutionary genetics -Statistical methods.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Book
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
        Dept. of Computational Biology and Bioinformatics Dept. of Computational Biology and Bioinformatics Processing Center 01/09/2015   572.838 GU-S DCB1939 01/09/2015 19/07/2019 Book