The Ten Most Wanted Solutions in Protein Bioinformatics (Record no. 293528)

MARC details
000 -LEADER
fixed length control field 02425nam a2200169Ia 4500
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781584884910
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572.6 TRA-T
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Anna Tramontano
245 ## - TITLE STATEMENT
Title The Ten Most Wanted Solutions in Protein Bioinformatics
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Boca Raton
Name of publisher, distributor, etc. Chapman & Hall/CRC
Date of publication, distribution, etc. 2005
300 ## - PHYSICAL DESCRIPTION
Extent 186 pages : illustrations (some color) ; 24 cm.
490 ## - SERIES STATEMENT
Series statement Chapman & Hall/CRC mathematical biology and medicine series.
505 ## - FORMATTED CONTENTS NOTE
Formatted contents note Problem 1. Protein sequence alignment -- Problem 2. Predicting protein features from the sequence -- Problem 3. Function prediction -- Problem 4. Protein structure prediction -- Problem 5. Membrane proteins -- Problem 6. Functional site identification -- Problem 7. Protein-protein interaction -- Problem 8. Protein-small molecule interaction -- Problem 9. Protein design -- Problem 10. Protein engineering.
520 ## - SUMMARY, ETC.
Summary, etc. Utilizing high speed computational methods to extrapolate to the rest of the protein universe, the knowledge accumulated on a subset of examples, protein bioinformatics seeks to accomplish what was impossible before its invention, namely the assignment of functions or functional hypotheses for all known proteins. \The Ten Most Wanted Solutions in Protein Bioinformatics\ considers the ten most significant problems occupying those looking to identify the biological properties and functional roles of proteins. Problem One considers the challenge involved with detecting the existence of an evolutionary relationship between proteins. Two and Three studies the detection of local similarities between protein sequences and analysis in order to determine functional assignment. Four, Five, and Six look at how the knowledge of the three-dimensional structures of proteins can be experimentally determined or inferred, and then exploited to understand the role of a protein.Seven and Eight explore how proteins interact with each other and with ligands, both physically and logically. Nine moves us out of the realm of observation to discuss the possibility of designing completely new proteins tailored to specific tasks. And lastly, Problem Ten considers ways to modify the functional properties of proteins. After summarizing each problem, the author looks at and evaluates the current approaches being utilized, before going on to consider some potential approaches.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Proteomics. Bioinformatics. Proteins.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Book
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
        Dept. of Computational Biology and Bioinformatics Dept. of Computational Biology and Bioinformatics Processing Center 01/09/2015   572.6 TRA-T DCB85 01/09/2015 01/09/2015 Book