MARC details
| 000 -LEADER |
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| fixed length control field |
02407cam a22003015i 4500 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783662442876 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
591.35 |
| Item number |
GUE-G |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Guénet, Jean Louis. |
| 245 10 - TITLE STATEMENT |
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| Title |
Genetics of the Mouse / |
| Statement of responsibility, etc. |
by Jean Louis Guénet, Fernando Benavides, Jean-Jacques Panthier, Xavier Montagutelli. |
| 250 ## - EDITION STATEMENT |
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| Edition statement |
1st ed. 2015. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource (XVII, 408 pages 106 illustrations, 44 illustrations in color.) |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Origins of the Laboratory Mouse -- Basic Concepts of Reproductive Biology And Genetics -- Cytogenetics -- Gene Mapping -- The Mouse Genome -- Epigenetic Control of Genome Expression -- Mutations and Experimental Mutagenesis -- Transgenesis and Transgenic Animals -- The Different Categories of Genetically Standardized Populations of Laboratory Mice -- Quantitative Traits and Quantitative Genetics. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided. In short, this book offers an essential resource for all scientists who use or plan to use mice in their research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Animal genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Animal models in research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Gene expression. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Genetic engineering. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Transgenic organisms. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Animal Genetics and Genomics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Animal Models. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Gene Expression. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Genetic Engineering. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Transgenics. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Benavides, Fernando. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Montagutelli, Xavier. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Panthier, Jean-Jacques. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Book |
