Mouse models of cancer : (Record no. 261250)

MARC details
000 -LEADER
fixed length control field 02486cam a2200253 i 4500
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781621820031 (pbk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781621820048 (case)
082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.027333
Item number MOU
245 00 - TITLE STATEMENT
Title Mouse models of cancer :
Remainder of title a laboratory manual /
Statement of responsibility, etc. edited by Cory Abate-Shen, Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, Columbia University Medical Center, Katerina Politi, Yale Cancer Center, Yale University School of Medicine, Lewis A. Chodosh, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Kenneth P. Olive, Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, Columbia University Medical Center.
300 ## - PHYSICAL DESCRIPTION
Extent xiv, 521 pages :
Other physical details illustrations (some color) ;
520 ## - SUMMARY, ETC.
Summary, etc. "The laboratory mouse is an important model for studying cancer and its treatment. This book includes both background information and step-by-step protocols for generating mouse models that accurately recapitulate many features of human cancer. It covers genetic models, including transgenic germline models, gene knockouts and knockins, and conditional and inducible systems, as well as models derived using chemical carcinogens, RNA interference, tissue recombination, and other strategies. Techniques to characterize tumor development, progression, and metastasis in these mice using state-of-the-art imaging, histopathological, surgical, and other approaches are described. The uses of these models in preclinical and translational research are also discussed"--
520 ## - SUMMARY, ETC.
Summary, etc. "99% of mouse protein-coding genes have an equivalent homolog in the human genome, despite the striking differences in appearance between mouse and man. This remarkable genetic similarity, together with our ability to finely engineer the murine genome, has made the mouse the ideal animal in which to model and analyze human biology and disease. This book envisages the next generation of mouse models, and it also addresses the strategic use of mice in the fight against cancer"--
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cancer
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice as laboratory animals.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SCIENCE / Life Sciences / Biology / Developmental Biology.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SCIENCE / Life Sciences / Biology / Molecular Biology.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MEDICAL / Oncology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Abate-Shen, Cory.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Politi, Katerina.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Chodosh, Lewis A.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Olive, Kenneth P.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Book
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
        Dept. of Biochemistry Dept. of Biochemistry Processing Center 12/01/2021   616.027333 MOU BCH3320 12/01/2021 12/01/2021 Book