A First Course in Systems Biology/ (Record no. 261106)

MARC details
000 -LEADER
fixed length control field 02450nam a22001577a 4500
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780815345688
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 570.15195
Item number VOI-F
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Voit , Eberhard O.
245 ## - TITLE STATEMENT
Title A First Course in Systems Biology/
Statement of responsibility, etc. Eberhard O. Voit
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. New York:
Name of publisher, distributor, etc. TAYLOR & FRANCIS,
Date of publication, distribution, etc. 2013.
300 ## - PHYSICAL DESCRIPTION
Extent 445 P.
505 ## - FORMATTED CONTENTS NOTE
Formatted contents note 1. Biological Systems 2. Introduction to Mathematical Modeling 3. Static Network Models 4. The Mathematics of Biological Systems 5. Parameter Estimation 6. Gene Systems 7. Protein Systems 8. Metabolic Systems 9. Signaling Systems 10. Population Systems 11. Integrative Analysis of Genome, Protein, and Metabolite Data: A Case Study in Yeast 12. Physiological Modeling: The Heart as an Example 13. Systems Biology in Medicine and Drug Development 14. Design of Biological Systems 15. Emerging Topics in Systems Biology
520 ## - SUMMARY, ETC.
Summary, etc. A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling, then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way, it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks, understanding the modern literature, and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design, limit cycles and chaos, parameter estimation in Excel, model representations of gene regulation through transcription factors, derivation of the Michaelis-Menten rate law from the original conceptual model, different types of inhibition, hysteresis, a model of differentiation, system adaptation to persistent signals, nonlinear nullclines, PBPK models, and elementary modes. The format is a combination of instructional text and references to primary literature, complemented by sets of small-scale exercises that enable hands-on experience, and large-scale, often open-ended questions for further reflection.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Systems biology. Computational biology. Systems Biology.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Book
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
        Dept. of Biochemistry Dept. of Biochemistry Processing Center 06/01/2021   570.15195 VOI-F BCH3121 06/01/2021 06/01/2021 Book