DNA repair and replication : mechanisms and clinical significance /

DNA repair and replication : mechanisms and clinical significance / edited by Roger J. A. Grand, John J. Reynolds. - Florida: CRC Press, 2019. - xvi, 348 pages : color illustrations ;

"A Garland Science book."

Includes bibliographical references.

DNA replication and cell cycle control / Sara Priego Moreno, Rebecca M. Jones, and Agnieszka Gambus -- DNA replication termination and genomic instability / Rebecca M. Jones, Sara Priego Moreno, and Agnieszka Gambus -- Mechanisms of DNA damage tolerance / Anastasia Zlatanou and Cyrus Vaziri -- Repair of DNA adducts and single strand breaks / Alicja Winczura and John J Reynolds -- Homologous recombination at replication forks / Eva Petermann -- Mechanisms of double strand break repair by non-homologous end-joining / Michal Malewicz -- Protein methylation and the DNA damage response / Martin Higgs and Clare Davies -- Ubiquitin, SUMO, and the DNA double strand break response / R.M. Densham, A.J. Garvin, and J.R. Morris -- Transcription in the context of genome stability maintenance / Marco Saponaro -- RNA binding proteins and the DNA damage response / Roger Grand -- DNA replication and inherited human disease / John J. Reynolds and Grant S. Stewart -- Genetics of ataxia telangiectasia and AT like disorders / A. Malcolm R. Taylor -- DNA repair mechanisms in stem cells and its implications during ageing / Rachel Bayley and Paloma Garcia -- Targeting replication stress in sporadic tumours / Marwan Kwok and Tatjana Stankovik.

9780815345992 (pbk. : alk. paper) 0815345992 (pbk. : alk. paper) 9781138612914 (hardback : alk. paper) 113861291X (hardback : alk. paper)


DNA Repair
DNA Replication
Genomic Instability
Molecular Targeted Therapy

572.8 / GRA-D