Chemical proteomics : methods and protocols /
Chemical proteomics : methods and protocols /
edited by Gerard Drews and Marcus Bantscheff.
- New York : Humana Press, c2012.
- xi, 313 p. : ill. ;
- Methods in Molecular Biology, Springer protocols .
Includes bibliographical references and index.
Mass spectrometry-based chemoproteomic approaches / Marcus Bantscheff -- Chemical proteomics in drug discovery / Gerard Drewes -- Compound immobilization and drug-affinity chromatography / Uwe Rix, Manuela Gridling, and Giulio Superti-Furga -- Affinity-based chemoproteomics with small molecule-peptide conjugates / Chaitanya Saxena -- A chemical proteomic probe for detecting dehydrogenases : catechol rhodanine / Xia Ge and Daniel S. Sem -- Probing proteomes with benzophenone photoprobes / Akira Kawamura and Doina M. Mihai -- Biotinylated probes for the analysis of protein modification by electrophiles / Simona G. Codreanu ... [et al.] -- Profiling of methyltransferases and other S-adenosyl-L-homocysteine-binding proteins by capture compound mass spectrometry / Thomas Lenz ... [et al.] -- Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC / Shao-En Ong ... [et al.] -- Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags / Carsten Hopf ... [et al.] -- Affinity-based profiling of dehydrogenase subproteomes / Xia Ge and DAniel S. Sem -- Probing the specificity of protein-protein interactions by quantitative chemical proteomics / Duangnapa Kovanich ... [et al.] -- Fluorescence-based proteasome activity profiling / Annamieke de Jong ... [et al.] -- Chemical cross-linking and high-resolution mass spectrometry to study protein-drug interactions / Mathias Q. Müller and Andrea Sinz -- Monitoring ligand modulation of protein-protein interactions by chemical cross-linking and high-mass MALDI mass spectrometry / Natalia Gasilova and Alexis Nazabal -- Time-controlled transcardiac perfusion crosslinking for in vivo interactome studies / Amy Hye Won Jeon and Gerold Schmitt-Ulms -- Ligand discovery using small-molecule microarrays / Dominick E. Casalena, Dina Wassaf, and Angela N. Koehler -- Working with small molecules : preparing and storing stock solutions and determination of kinetic solubility / Andrea Wolf, Satoko Shimamura, and Friedrich B.M. Reinhard -- A database for chemical proteomics : ChEBI / Paula de Matos ... [et al.] -- Working with small molecules : rules-of-thumb of drug likeness / Ming-Qiang Zhang.
9781617793639 (alk. paper) 1617793639 (alk. paper)
Proteomics--Laboratory manuals.
Biochemistry--Laboratory manuals.
Proteomics--Laboratory Manuals.
Chemistry Techniques, Analytical--Laboratory Manuals.
Biochemistry--Laboratory Manuals.
572.6 DRE
Includes bibliographical references and index.
Mass spectrometry-based chemoproteomic approaches / Marcus Bantscheff -- Chemical proteomics in drug discovery / Gerard Drewes -- Compound immobilization and drug-affinity chromatography / Uwe Rix, Manuela Gridling, and Giulio Superti-Furga -- Affinity-based chemoproteomics with small molecule-peptide conjugates / Chaitanya Saxena -- A chemical proteomic probe for detecting dehydrogenases : catechol rhodanine / Xia Ge and Daniel S. Sem -- Probing proteomes with benzophenone photoprobes / Akira Kawamura and Doina M. Mihai -- Biotinylated probes for the analysis of protein modification by electrophiles / Simona G. Codreanu ... [et al.] -- Profiling of methyltransferases and other S-adenosyl-L-homocysteine-binding proteins by capture compound mass spectrometry / Thomas Lenz ... [et al.] -- Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC / Shao-En Ong ... [et al.] -- Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags / Carsten Hopf ... [et al.] -- Affinity-based profiling of dehydrogenase subproteomes / Xia Ge and DAniel S. Sem -- Probing the specificity of protein-protein interactions by quantitative chemical proteomics / Duangnapa Kovanich ... [et al.] -- Fluorescence-based proteasome activity profiling / Annamieke de Jong ... [et al.] -- Chemical cross-linking and high-resolution mass spectrometry to study protein-drug interactions / Mathias Q. Müller and Andrea Sinz -- Monitoring ligand modulation of protein-protein interactions by chemical cross-linking and high-mass MALDI mass spectrometry / Natalia Gasilova and Alexis Nazabal -- Time-controlled transcardiac perfusion crosslinking for in vivo interactome studies / Amy Hye Won Jeon and Gerold Schmitt-Ulms -- Ligand discovery using small-molecule microarrays / Dominick E. Casalena, Dina Wassaf, and Angela N. Koehler -- Working with small molecules : preparing and storing stock solutions and determination of kinetic solubility / Andrea Wolf, Satoko Shimamura, and Friedrich B.M. Reinhard -- A database for chemical proteomics : ChEBI / Paula de Matos ... [et al.] -- Working with small molecules : rules-of-thumb of drug likeness / Ming-Qiang Zhang.
9781617793639 (alk. paper) 1617793639 (alk. paper)
Proteomics--Laboratory manuals.
Biochemistry--Laboratory manuals.
Proteomics--Laboratory Manuals.
Chemistry Techniques, Analytical--Laboratory Manuals.
Biochemistry--Laboratory Manuals.
572.6 DRE